Proliferation of Human Mononuclear Cells with 3H-Thymidine

Wikis > Proliferation of Human Mononuclear Cells with 3H-Thymidine
When an antigen or mitogen is presented by antigen presenting cell (APC), specific T-cells can recognize and respond to these antigens or mitogens. They will start dividing (proliferation) and can also release specific cytokines and chemokines. The proliferation can be detected by adding 3H thymidine to the dividing cells. This 3H is incorporated into the DNA only during replication of a cell (1). The uptake is thus proportional to the number of cell divisions.

Proliferation of Human Mononuclear Cells with 3H-Thymidine

 

  
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