Introducing the van Loosdregt-Vastert research group








Bas Vastert (pediatric rheumatologist/scientist) and Jorg van Loosdregt (fundamental scientists) have joined forces to, together, lead the pediatric rheumatology research group in the University Medical Center Utrecht (The Netherlands). Our mission is to increase our understanding of the molecular mechanisms underlying Juvenile Idiopathic Arthritis (JIA), and translating these findings into novel therapeutics. JIA is a chronic autoimmune disease that affects 1/1000 children and can lead to severe loss of quality of life. Our group combines both fundamental and clinically orientated research projects. We believe that bringing these fields of research, and researchers, together facilitates translational research allowing for more efficient transition of experimental findings to the clinic.

More specifically, our research projects focus on:

-Understanding the contribution of epigenetics in JIA pathogenesis.

-Identification of novel therapeutic targets for the treatment of JIA.

-Clinical trials to improve JIA treatment.